Novel therapy for hair loss

Androgenetic alopecia (AGA) is a genetically-determined progressive hair-loss condition and the most common cause of hair loss in men. In addition to hormone-dependent changes in the hair growth cycle, chronic microscopic inflammation in the hair follicles contributes to the condition. Due to the chronic nature of AGA, treatment should be started early and continued indefinitely. Otherwise, the benefit will not be maintained upon discontinuing therapy.

To date, only two medications have been approved by the FDA for the treatment of AGA: topical minoxidil and oral finasteride. However, there are other topical and systemic treatment options to address the many underlying mechanisms involved in AGA. In the search for alternatives to oral finasteride and topical minoxidil, melatonin—a potent antioxidant and growth modulator—has been identified as a promising treatment for AGA. In addition to melatonin, ginkgo biloba has pronounced anti-oxidative properties and a positive impact on hair growth by providing the hair roots with better nutrients. Furthermore, biotin, which is an important micronutrient, can support hair growth.

Five clinical studies were conducted using a European topical solution called Asatex containing melatonin, ginkgo biloba, and biotin. All five studies showed significant positive effects in the treatment of hair loss in both men and women while showing good tolerability.

Comments: If you wish to make your own hair-loss topical preparation, mix equal parts liquid Melatonin made by Svasthya Body & Mind, liquid Gingko Biloba made by Nature’s Answer, and liquid Biotin made by Honeycombs Industries. All three products are alcohol-free (very important) and can be found on Amazon.com.